Maternal Mortality Ratio Down 40% in Bangladesh

first_img ShareEmailPrint To learn more, read: Posted on February 17, 2011November 13, 2014Click to share on Facebook (Opens in new window)Click to share on Twitter (Opens in new window)Click to share on LinkedIn (Opens in new window)Click to share on Reddit (Opens in new window)Click to email this to a friend (Opens in new window)Click to print (Opens in new window)In nine years, between 2001 and 2010, the maternal mortality ratio (MMR) in Bangladesh declined by 40% according to a survey supported by USAID, MEASURE Evaluation and ICDDR,B.The survey found that Bangladesh’s MMR dropped from 322 deaths per 100,000 live births to 194 deaths per 100,000 live births. According to UNDP, Bangladesh was not on track to meet MDG5, but it is certainly getting closer to its target of an MMR of 144 in 2015.Share this:last_img read more

Researchers study efficacy and safety of new treatment for OUD

first_img Source:http://www.uky.edu/ Jul 20 2018Better delivery of medications to treat opioid use disorder (OUD) is key to addressing the opioid crisis and helping the 2.6 million Americans affected by the disease. While their medications, such as buprenorphine, exist to treat the symptoms of withdrawal and stave off cravings their formulation is primarily taken sublingually, in the form of pills and films. Despite being effective and efficacious in treating OUD, the formulation has limitations such as misuse and nonadherence, diversion and the possibility of unintended pediatric exposures.In an article recently published in the Journal of the American Medical Association, Dr. Michelle Lofwall, associate professor of Psychiatry and Sharon Walsh, director of the UK Center on Drug and Alcohol Research, studied the efficacy and safety of buprenorphine delivered as a weekly or monthly injection, CAM2038 a fluid crystal depot buprenorphine therapy for moderate-to-severe OUD.Related StoriesNutritional supplements offer no protection against cardiovascular diseases, say researchersE-cigarettes much more effective for traditional cigarettes finds studyComputer-generated flu vaccine enters clinical trials in the USIn the 24-week, double-blind, double-dummy, active-controlled, randomized clinical trial participants at 35 outpatient clinics were placed in two groups, one of which received buprenorphine injections and a daily sublingual placebo and a second group which received placebo buprenorphine injections and daily sublingual buprenorphine-naloxone tablets.The study compared the performance of weekly and monthly CAM2038, with the current standard of care, a daily sublingual dose of buprenorphine/naloxone. Results showed the drug’s non-inferiority on the primary responder rate outcome, which was based upon highly sensitive urine testing detecting illicit opioids. The data suggests that injectable buprenorphine is efficacious and may have advantages.The results of this study will aid in improving access to treatment for many and reduce adverse risks of traditional buprenorphine. Lofwall said, “Together with the six-month buprenorphine implant, these new long-acting medication delivery systems would allow us to administer a proven medication to the patients directly, ensuring adherence, leading to improved medication efficacy as well as avoiding the potential for missed or stolen doses, diversion or accidental pediatric exposure, which are significant public health concerns.”last_img read more