Transplant, Take 2: In search of a kidney donor

first_imgShare on Facebook Tweet on Twitter Save my name, email, and website in this browser for the next time I comment. Free webinar for job seekers on best interview answers, hosted by Goodwill June 11 Support conservation and fish with NEW Florida specialty license plate Please enter your name here You have entered an incorrect email address! Please enter your email address here Please enter your comment! TAGSFlorida Hospital – Apopka Previous articleHappy Earth Day! 5 Books to Read to Celebrate the PlanetNext articleFood for Thought: Cooking for Your Heart Denise Connell RELATED ARTICLESMORE FROM AUTHOR The Anatomy of Fear LEAVE A REPLY Cancel reply From Florida Hospital ApopkaKen Eckstein needed a match. No, he wasn’t in search of a soulmate; he was desperate for a kidney donor.For a patient with kidney failure, life on the transplant waiting list is full of hope, disappointment, and frustration, Ken says, as well as the daily drain of dialysis. He knew the process well, having gone through his first transplant as a teenager in the early ‘90s.Ken has a rare disease called focal segmental glomerulosclerosis (FSGS) that also affects his sisters, Christine and Susan. It attacks the glomeruli, small blood vessels in the kidneys. Just as a filter keeps coffee grounds in, glomeruli filter the blood, removing waste and excess fluids (which become urine) while leaving needed protein behind in the body. Damaged or scarred glomeruli allow the protein to leak into the urine. When medications or other treatments fail, a kidney transplant may be the only option.In 2010, when Ken went on dialysis waiting for another kidney, the initial outlook for finding a match was bleak.“I remember doctors telling me that because of my first transplant I’d never get another,” he says.Why Second Transplants are TougherKen’s second transplant posed greater challenges because of antibodies, proteins produced by white blood cells to help the body fight infections.Antibodies are the first line of defense in the immune response, but they can also treat any foreign tissue, such as a transplanted kidney, as a threat. And people who have had additional exposure to foreign tissue (such as through blood transfusions, transplants or pregnancy) have more antibodies in their blood, making it harder to find a compatible donor. Having a high level of antibodies in the body is called being “sensitized.”To measure a patient’s sensitization, he or she is given a panel reactive antibody (PRA) test. A person with a PRA score of higher than 20 percent is considered sensitized. A sensitized patient may have to wait significantly longer for a transplant or might not receive one at all.Blood tests found Ken’s PRA to be 60 percent, meaning he was sensitized against 60 percent of the general population. Ken felt that his chances of finding a kidney his body wouldn’t reject were like finding a needle in a haystack.That is until he met Bobby Nibhanupudy, MD, the medical director of abdominal transplant at the Florida Hospital Transplant Institute. He implemented the kidney desensitization program at Florida Hospital, which likely saved Ken’s life.How Kidney Desensitization WorksThe idea behind the program — one of the few that exist nationally — is to lower the PRA percentage enough that finding a match becomes more likely. At the time Ken entered the program, he didn’t know much about the treatment, but he was ready to do anything to save his life.“I’m one of those people who goes full throttle,” he says. “I was on dialysis at 19. I knew what it was like and I was ready to move forward and was praying that it was going to work.”A key component of the treatment is IVIG, or intravenous immunoglobin, a blood product containing pooled antibodies extracted from the plasma of thousands of blood donors. Beginning in September 2010, Ken began his IVIG treatment. For two days each month, a nurse from Ocala would drive to Ken’s home in Tampa and slowly inject the IVIG into his bloodstream for four to six hours. They would eat lunch, watch movies and chat while she monitored Ken’s vitals. He was simultaneously undergoing home dialysis administered by his sister, Christine, and crossing his fingers that the IVIG treatment, which initially wasn’t covered by his insurance, would help him find a donor.After three months of IVIG, Ken got a call that would change his life. His PRA had lowered enough to make his brother, Rick, a positive match. He got his new kidney on December 8, 2010.Paving the Path for Other Patients“Honestly, IVIG saved my life,” Ken says. “I really hope this is something that becomes part of the protocol for all kidney patients, but it’s especially critical for second transplant patients.”Dr. Bobby agrees. “This treatment [IVIG] serves a population that has been a growing issue in transplantation for some time,” he says. “There are still methods we can explore to speed up the process, but we’re moving forward.”Ken is especially thankful for the successful treatment because it’s likely that his sisters will need it in the future. Christine (pictured above) has a transplanted kidney that is doing well, but Susan’s is failing, and her chances of being highly sensitized are probable, Ken says. Thanks to Dr. Bobby’s program, kidney patients like Ken and his sisters now have a fighting chance for transplantation.last_img read more

Delinquencies Increase in Hurricane Impacted States

first_img Demand Propels Home Prices Upward 2 days ago Radhika Ojha is an independent writer and copy-editor, and a reporter for DS News. She is a graduate of the University of Pune, India, where she received her B.A. in Commerce with a concentration in Accounting and Marketing and an M.A. in Mass Communication. Upon completion of her masters degree, Ojha worked at a national English daily publication in India (The Indian Express) where she was a staff writer in the cultural and arts features section. Ojha, also worked as Principal Correspondent at HT Media Ltd and at Honeywell as an executive in corporate communications. She and her husband currently reside in Houston, Texas. Delinquencies Increase in Hurricane Impacted States Sign up for DS News Daily Servicers Navigate the Post-Pandemic World 2 days ago The Week Ahead: Nearing the Forbearance Exit 2 days ago Previous: Why Homeowners are Losing Sleep Over Rising Debt Next: HUD Approves U.S. Virgin Islands Disaster Recovery Plan The Best Markets For Residential Property Investors 2 days ago Home / Daily Dose / Delinquencies Increase in Hurricane Impacted States Demand Propels Home Prices Upward 2 days ago Serious delinquencies in Texas and Florida increased significantly, according to the Loan Performance Insights report released by CoreLogic on Tuesday. The report, which looks at foreclosure and delinquency activity reported in April 2018 found that the percent of loans 90 days or more delinquent or in foreclosure in these states more than doubled in April, compared with where they were in the Fall of 2017 when the hurricanes struck. The 90-day-plus delinquent or in-foreclosure rate has also quadrupled in Puerto Rico.”Delinquency rates are nearing historic lows except in areas impacted by extreme weather over the past 18 months, reflecting a long period of strict underwriting practices and improved economic conditions,” said Frank Martell, President, and CEO of CoreLogic. “Last year’s hurricanes and wildfires continue to affect today’s default rates.”At a national level though, the share of home loans transitioning from current to 30 days past due was the lowest for April since 2000. CoreLogic said that early-stage delinquencies were declined to 1.8 percent in April compared with 2.2 percent last year. The share of mortgages that were 60 to 89 days past due remained unchanged on a year-over-year basis at 0.6 percent, while serious delinquency rates, including loans in foreclosure, were slightly down from a year ago at 1.9 percent. The April 2018 serious delinquency rate was the lowest for that month since 2007 when it was 1.6 percent.“Job growth, home-price appreciation, and full-doc underwriting have pushed delinquency and foreclosure rates to the lowest point in more than a decade,” said Dr. Frank Nothaft, Chief Economist for CoreLogic.The report indicated that nationally, 4.2 percent of mortgages were in some stage of delinquency in April 2018. This represented a 0.6 percentage point decline in the overall delinquency rate compared with the same period last year when it was 4.8 percent.In April, the report revealed, foreclosure inventory rate was 0.6 percent, down a percentage point from 0.7 percent in April 2017. This compares with the lowest level of foreclosure inventory in June 2007.Learn more about the impact of hurricanes on housing:The Lingering Impact of Hurricane Maria on Puerto RicoHUD Approves Florida Disaster Plan—What You Need to Know Share Save Related Articles Tagged with: CoreLogic default Delinquency Foreclosure Hurricane Irma Maria Serious Delinquencycenter_img Data Provider Black Knight to Acquire Top of Mind 2 days ago  Print This Post The Best Markets For Residential Property Investors 2 days ago Governmental Measures Target Expanded Access to Affordable Housing 2 days ago July 10, 2018 2,011 Views Data Provider Black Knight to Acquire Top of Mind 2 days ago Servicers Navigate the Post-Pandemic World 2 days ago About Author: Radhika Ojha CoreLogic default Delinquency Foreclosure Hurricane Irma Maria Serious Delinquency 2018-07-10 Radhika Ojha Governmental Measures Target Expanded Access to Affordable Housing 2 days ago in Daily Dose, Featured, Foreclosure, News Subscribelast_img read more